TRITOM WEBINAR: DESIGNER AND TARGETED CONTRAST AGENT FOR PHOTOACOUSTIC IMAGING
DESIGNER AND TARGETED CONTRAST AGENT FOR PHOTOACOUSTIC IMAGING
Date: October 19, 2022
Time: 09:00 PM (CST)
Overview:
The talk will focus on the synthesis, characterization, and use of a novel contrast agent composed of indocyanine green dye for NIR-I photoacoustic imaging. The contrast agent can be easily tuned to different sizes without enclosure in nanocarriers, has strong optical absorption and PA signal at 895 nm, can be easily functionalized with different targeting molecules, and can be imaged for 120 minutes in vivo. The presentation will explain details on the genesis of the idea for building a biocompatible contrast agent and give details on its easy synthesis protocols, touch upon a functionalization scheme for adding targeting molecules, and demonstrate its use as a PA contrast in mice using the TriTom small animal imaging system.
In this webinar, we will present a synthesis method for clinically translatable ICG-JA whose mean size can be finely tuned from 200 nm to 1000 nm and that does not require encapsulation in a nanocarrier. The talk will also detail the complete characterization of the agent and steps for functionalization with targeting peptides or antibodies. Additionally, the webinar will also provide details about the PA properties of the contrast in vitro in different conditions including whole blood, followed by details on the photoacoustic imaging in vivo using the TriTom system.
Learning Objectives:
- The audience will get details on the synthesis of an NIR contrast agent without the need for a nanocarrier.
- They can learn in detail about what characteristics a contrast agent should possess to qualify as a clinically translatable technology.
- The audience will also be familiar with methods to create a targeted contrast agent.
- The audience will also see the use of this contrast agent in imaging small animals such as mice and its compatibility with a system such as the TriTom.
LEGION AMP WEBINAR: DUAL-MODALITY X-RAY-INDUCED RADIATION ACOUSTIC AND ULTRASOUND IMAGING FOR REAL-TIME MONITORING OF RADIOTHERAPY
DUAL-MODALITY X-RAY-INDUCED RADIATION ACOUSTIC AND ULTRASOUND IMAGING FOR REAL-TIME MONITORING OF RADIOTHERAPY
Date: October 19, 2022
Time: 09:00 PM (CST)
Overview:
This is the third webinar of the Legion AMP webinar series, hosted by PhotoSound Technologies. This webinar covers dual-modality, ultrasound, and thermoacoustic imaging in real-time, while using an ionizing radiation source, for the purpose of monitoring radiation therapy, as presented by Dr. Wei Zhang from the Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, USA. During the introduction, Sam Toler, System Test Engineer I, provides a brief explanation of how the Legion AMP can optimize the SNR and low-frequency bandwidth of your photoacoustic/thermoacoustic system.
Topics Covered:
- Legion Amp design
- Legion Amp motivation
- Legion Amp noise measurements
- Legion Amp variations
- Objective of Studies
- Legion Amp demo
- Results of studies
About The Speakers
Sam Toler
System Test Engineer I
Sam Toler earned his bachelor of science degree in Biomedical Engineering from Texas A&M University. No matter if it’s software or hardware, as the Systems Test Engineer, Sam Toler strives to ensure quality products. As the main contact for technical support, he handles all service requests and inquiries with care and due diligence. In the background, he utilizes his hands-on experiences with microcontrollers, electronics, and software to improve quality systems during design and production.
Wei Zhang, Ph.D.
Research Fellow, Biomedical Engineering
Wei Zhang is a Research Investigator at the Department of Biomedical Engineering, University of Michigan. He received his master’s degree and Ph.D. degree in the institution of Biomedical Engineering, Peking Union Medical College, Beijing, China. He finished his postdoc training at the Department of Biomedical Engineering at the University of Michigan. Dr. Zhang’s research focused on developing novel techniques for radiation dose imaging and ocular imaging. His research interests include radiation acoustic imaging, photoacoustic imaging, and multi-modality imaging.
LEGION AMP WEBINAR: FIBER TIP TRACKING WITH PHOTOACOUSTIC IMAGING BY USING LEGION AMP
FIBER TIP TRACKING WITH PHOTOACOUSTIC IMAGING BY USING LEGION AMP
Date: March 24, 2022
Time: 07:00 PM (CST)
Overview:
The Legion AMP webinar series is hosted by PhotoSound Technologies Marketing Specialist Sarah Argo. In the second webinar of the Legion Amp Webinar Series, Samuel Toler (System Test Engineer I), discussed the Legion Amp design, motivation, and benefits in relation to how it could optimize your research. Samuel John and Dr. Yan Yan, from the Photoacoustic & Ultrasonic Research & Engineering (PURE) Laboratory, led by Dr. Mohammad Mehrmohammadi at Wayne State University, share a live demonstration of the Legion Amp along with their research to cover fiber tip tracking with photoacoustic imaging by using the Legion Amp.
Topics Covered:
- Legion Amp design
- Legion Amp motivation
- Legion Amp noise measurements
- Legion Amp variations
- Objective of Studies
- Legion Amp demo
- Results of studies
About the Speakers
Sam Toler
System Test Engineer I
Sam Toler earned his bachelor of science degree in Biomedical Engineering from Texas A&M University. No matter if it’s software or hardware, as the Systems Test Engineer, Sam Toler strives to ensure quality products. As the main contact for technical support, he handles all service requests and inquiries with care and due diligence. In the background, he utilizes his hands-on experiences with microcontrollers, electronics, and software to improve quality systems during design and production.
Yan Yan, Ph.D.
Postdoc @Wayne State University Integrative Bioscience Center
Dr. Yan Yan is a research scientist from the Photoacoustic & Ultrasonic Research & Engineering (PURE) Laboratory, led by Dr. Mohammad Mehrmohammadi at Wayne State University. He holds a bachelor’s degree in Computer Science and Telecommunication from the Post and Telecommunication of Chongqing University, a master’s degree in Computer Science, and a doctorate in Biomedical Engineering from Wayne State University. His research focused on developing the new generation, multi-parametric acoustic imaging device for fetal and maternal care. His areas of interest are Medical Device Development, Medical Image, Machine Learning, and Data Mining.
Samuel John
M.S, PhD student @Wayne State University Integrative Bioscience Center
Samuel John is a 4th year PhD student in the Functional and Molecular Ultrasound Research Laboratory at Wayne State University. He is also currently pursuing the dual-title degree in Biomedical Imaging. He has completed his master’s in biomedical engineering in Wayne State University. His research is focused on utilizing photoacoustic imaging for enhancing image guided procedures. He has also published several journals and conference proceedings related to photoacoustic imaging for image-guided procedures: https://scholar.google.com/citations?user=cZaIDRMAAAAJ&hl=en He has also served as a reviewer for IEEE Access journal (https://publons.com/researcher/3489407/samuel-john/). Two patent disclosures have been filed on his research works. He is the recipient of the dual title program in biomedical imaging. He has won many hackathons, poster competitions, conducts microcontroller design workshops for students.
LEGION AMP WEBINAR: COMPARATIVE EVALUATION OF A NIR-II NANOPARTICLE WITH AND WITHOUT THE LEGION AMP
COMPARATIVE EVALUATION OF A NIR-II NANOPARTICLE WITH AND WITHOUT THE LEGION AMP
Date: December 7, 2021
Time: 09:00 AM (CST)
Overview:
The Legion AMP webinar series is hosted by PhotoSound Technologies Marketing Specialist Sarah Argo. In the first webinar of the Legion Amp Webinar Series, Sergey Ermilov (CEO), discussed the Legion Amp design, motivation, and benefits in relation to how it could optimize your research. Vinoin Devpaul Vincely, from Carolyn Bayer’s lab at Tulane University, shares a live demo of the Legion Amp along with his research to cover the Comparative Evaluation of a NIR-II Nanoparticle with and Without the Legion Amp.
Topics Covered:
- Legion Amp design
- Legion Amp motivation
- Legion Amp noise measurements
- Legion Amp variations
- Objective of Studies
- Legion Amp demo
- Results of studies
About The Speakers
Sergey Ermilov has been the company’s Chief Executive Officer since it was founded in 2015. He has deep and multilateral experience in entrepreneurship, startup development, business operations and strategy with domain expertise in Biomedical Imaging. In addition to his formal business education in Strategic Management, in 2014 and 2019 he was leading startup teams in the NIH I-Corps™ business training programs. His business duties at PhotoSound include executive leadership, strategic business development, and direct working with top clients and partners. As a current President of the Board of Directors at PhotoSound, he also leads strategic business operations, financing, and represents the company in all top-level negotiations. Having a PhD in Bioengineering and world-class scientific expertise in Biomedical Optics, Dr. Ermilov also leads the research instrumentation projects at the current startup phase of the company.
VINOIN DEVPAUL VINCELY
Ph.D. Candidate | Biomedical Functional Imaging Lab
A Biomedical Engineering Ph.D. student at Tulane University, passionate about developing effective imaging technologies to improve medical diagnostic capabilities. Eager to push the frontiers of human knowledge and apply it to better healthcare.
